DM1 (CAT#: ADC-P-033)
ADCs Toxins, DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Product Information
- CAS NO
- 139504-50-0
- Description
- ADCs Toxins, DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
- Classification
- Microtubule Inhibitors
- Molecular Weight
- 738.29
- Purity
- 95%
For Research Use Only. NOT FOR CLINICAL USE.
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Customer Reviews
FAQ
Excellent
DM1 from Creative Biolabs has been a key asset in our ADC research. The high potency and specificity of this tubulin inhibitor significantly enhanced our ability to target and kill cancer cells effectively.
Excellent
We achieved excellent results using DM1 from Creative Biolabs. The product's consistent potency in disrupting microtubule function improved the efficacy of our antibody-drug conjugates in targeted cancer therapies.
Excellent
Creative Biolabs' DM1 provided superior performance in our ADC experiments. Its ability to inhibit microtubules efficiently led to strong cytotoxic effects in cancer cells, making it a reliable choice for our research.
Excellent
The use of DM1 from Creative Biolabs in our ADC projects resulted in potent cytotoxicity and precise targeting of cancer cells. The product's stability and effectiveness were consistently impressive throughout our experiments.
Excellent
Creative Biolabs' DM1 is an excellent choice for ADC research. The compound's ability to disrupt microtubule dynamics with high specificity has improved our targeted cancer cell destruction in multiple assays.
Excellent
We've been very pleased with the performance of Creative Biolabs' DM1 in our research. The tubulin inhibitor consistently provided strong cytotoxicity and improved the outcomes of our ADC-based therapies against various cancer types."
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