Tag Archives: Bispecific Antibody Development

30Mar/21

Overview of Bispecific Antibody Drug Technology (Part II)

March 30, 2021Bispecific Antibody ResearchBispecific Antibody, Bispecific Antibody Development, bsAbbiobsab

Distinctive BsAb Platform The problem of chain mismatches will reduce the yield of the bsAb, increase the difficulty of purification, and increase the production cost. Therefore, obtaining a correctly assembled bsAb hasRead More…

16Oct/20

Fig. 1 The classical IgG structure and schematic representations of several crucial bsAb formats. (Li, 2020)

Difficulties and Prospects in the Research and Development of Bispecific Antibodies

October 16, 2020Bispecific Antibody Clinic, Bispecific Antibody ResearchBispecific Antibody, Bispecific Antibody Development, bsAbbiobsab

Nowadays, in the tide of research and development of biological agents, antibody drugs are in an explosive period. The major monoclonal antibody (McAb) drugs have accounted for more than half of theRead More…

06Aug/20

Fig. 1 | Timeline of conceptual and technical innovations contributing to the development of the therapeutic bsAb landscape. (Labrijn, 2019)

How to Develop A Qualified Bispecific Antibody

August 6, 2020Bispecific Antibody Clinic, Bispecific Antibody ResearchBispecific Antibody Development, bsAbbiobsab

In 1960, Nisonoff and his collaborators at the Roswell Park Memorial Institute in New York first proposed the original concept of bispecific antibodies (BsAbs). Since then, with the great progress in theRead More…