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Category Archives: TCR Research

26Apr/24

High-throughput Discovery of Tumor-Reactive T Cell Receptors: Advancing Personalized Cellular Immunotherapy

April 26, 2024Cancer Immunotherapy, TCR ResearchPersonalized Cellular Immunotherapy, TCR engineered T cell, Tumor-Reactive T Cell Receptorbiocart

T-cell receptor (TCR) gene therapy is a form of cellular immunotherapy where peripheral blood T cells from cancer patients are genetically engineered ex vivo to express tumor-specific TCRs before being reintroduced intoRead More…

18Nov/22

CAR-T Cells Targeting Tumor Macrophages Show Promise for Treating a Range of Solid Tumors

November 18, 2022Chimeric Antigen Receptor Research, TCR ResearchCAR-T, Macrophagebiocart

In a recent study, researchers from the Icahn School of Medicine at Mount Sinai show that a new cancer immunotherapy that uses one type of immune cell to kill another type ofRead More…

10Jun/22

CAR-T Cells Targeting CD123 Specifically Kill Acute Myeloid Leukemia Cells

June 10, 2022TCR ResearchCAR-T, CAR-T therapy, CD123 CAR-Tbiocart

In a new preclinical study, researchers from Weill Cornell Medicine found that genetically engineered T cells successfully targeted specific cancer cells that may lead to relapse in acute myeloid leukemia (AML), andRead More…

20Aug/18

FDA Approved CAR-macrophage Therapy of Ovarian Cancer into Clinical Trials

August 20, 2018News, TCR ResearchCAR-T therapy, CARMA technology platform, Chimeric antigen receptorbiocart

Recently, MaxCyte announced that the company’s chimeric antigen receptor (CAR) cell therapy for the treatment of solid tumors based on non-viral messenger RNA (mRNA) technology has been approved by the Food andRead More…

22Nov/17

FDA approval brings first gene therapy to the United States…

November 22, 2017TCR ResearchCAR-T, CAR-T therapiesbiocart

“First CAR T-cell Therapy – Kymriah created from Novartis was approved by the FDA in August 2017. Two months later, Yescarta developed by Kite Pharma, Inc) is the second gene therapy approvedRead More…

22Nov/17

The Application of CAR-T in Disease Treatment

November 22, 2017Chimeric Antigen Receptor Research, TCR ResearchCAR-T, TCRbiocart

Chimeric antigen receptor (CAR) modified T cells (CAR-T) as a new field of adoptive immune cell therapy has become a hot spot in recent research. In 1989, Israeli scholar Gross et al.Read More…

22Nov/17

Comparison between CAR-T and TCR-T

November 22, 2017Chimeric Antigen Receptor Research, TCR ResearchCAR-T, TCRbiocart

As a matter of fact, tumor immunotherapy is divided into two categories. One is to show immune cells the tumor features, then direct them to locate and kill tumor cells. And anotherRead More…

22Nov/17

A New Immunotherapy Called CAR-T Will Beat Cancer Surprisingly

November 22, 2017TCR Researchbiocart

CAR-T (Chimeric Antigen Receptor T-Cell), as an immunocytotherapy regimen, has attracted a lot of attention from academics, doctors, patients, and investors worldwide. What does make it so attractive and popular? CAR-T modifies humanRead More…

22Nov/17

The Introduction of T Cell Proliferation Assay

November 22, 2017TCR ResearchCAR-T, TCRbiocart

Cell proliferation is an important vital sign of the organism in a splitting manner. Single-celled organisms produce new individuals in the form of cell division, while a multicellular organism that produces newRead More…

22Nov/17

TCR, A New Star of Immune Cell Therapy

November 22, 2017TCR ResearchCAR-T, TCRbiocart

Immune cell therapy, the fourth major cancer treatment following surgery, radiotherapy, and chemotherapy, has been recognized as the most active and promising treatment in the comprehensive tumor treatment in the 21st century.Read More…

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Recent Posts

  • CAR-T Cells Targeting PSCA Show Promise in Treating Metastatic Castration-Resistant Prostate Cancer
  • Advancements and Challenges in CAR-Macrophage Therapy: A New Frontier in Cancer Immunotherapy
  • NK Cell Surveillance Limits T Cell Responses: Implications for Cancer Immunotherapy
  • High-throughput Discovery of Tumor-Reactive T Cell Receptors: Advancing Personalized Cellular Immunotherapy
  • Overcoming Resistance: Enhancing CAR-T Therapy for AML with TP53 Mutations

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