Glycoproteins are essential biomolecules that perform a variety of functions across cellular systems, including structural roles, enzymatic activities, signaling pathways, and immune defense mechanisms. Central to glycoprotein functionality is glycosylation, the attachmentRead More…
Recent Advances and Applications in Glycoprotein Synthesis
Glycoproteins play a critical role in numerous biological processes, including cellular communication, immune regulation, and protein folding. The precise synthesis of these biomolecules is key to advancing fields like biotechnology, therapeutics, andRead More…
Therapeutic Glycoproteins: Advances in Research and Potential Applications
Therapeutic glycoproteins are increasingly recognized as pivotal in modern medical research, offering promising new treatments for a range of diseases. Recent advancements have provided deep insights into their structure, function, and potentialRead More…
Glycoprotein Production in Mammalian Cells
Abstract Over the past few years, the biopharmaceutical industry has increasingly utilized mammalian cell expression systems for producing biologics. The current state of glycosylation mechanisms in these systems, along with the factRead More…
Recent Progress in Glycobiology Microarray Research
Introduction Glycobiology microarrays are essential tools for high-throughput analysis of glycan-protein interactions. With continuous advancements, these arrays are facilitating a deeper understanding of immune responses, cancer diagnostics, drug discovery, and infectious diseaseRead More…
[Cell Host] Production of Therapeutic Glycoproteins in Mammalian Cells
Over the past few years, mammalian cell expression systems have gained attention in the biopharmaceutical industry for producing biologics. The current status of glycosylation mechanisms in these systems, coupled with the prevalenceRead More…
Effects of N-glycosylation on therapeutic protein stability, pharmacokinetics, and immunogenicity
N-glycosylation is one of the major post-translational modifications in nature, and its influence on protein structure and function is very important. N-glycosylation is mainly produced by the co-translational process of the endoplasmicRead More…