1. There are 102 EGFR-targeted drugs that are approved globally and in clinical research in total. Up to now, there are 20 EGFR-targeted drugs approved by the global market (Europe, USA, Japan,Read More…
According to the Journal of the American Medical Association, there were 15.4 million cancer patients worldwide in 2013. Among them, the cancer mortality rate in developing countries was higher than that ofRead More…
Before we start to introduce the principle of antibody diversity, you’d better learn about structure of antibody. Antibody consists of two heavy chains and two light chains. Most antibody related research isRead More…
Let’s see the other five Top 10 Best Selling drugs ranking from 6th to 10th. 6. Trastuzumab Trastuzumab (trade name: Herceptin) is a humanized monoclonal antibody. It targets HER2, blocks the functionRead More…
With Trump’s coming into power and the economic upheavals of Europe, the new drug approved by the FDA fell to a record low in 2016, following which the drug market of 2017Read More…
What is antibody (conventional antibody)? Before we begin to introduce recombinant antibody, we should learn about antibody. Antibody is known as immunoglobulins which are generally Y-shaped. They are peptide molecule secreted byRead More…
Phage display has proven to be a powerful technique for the interrogation of libraries containing millions or even billions of different peptides or proteins. Phage display libraries permit the selection of peptidesRead More…
Introduction Single domains represent the smallest known fragment still capable of binding antigen that can be isolated from a full-sized immunoglobulin. In work on the cloning of antibody genes and construction ofRead More…
The phage display technology, first described over a decade ago, has opened new windows in the production of recombinant antibody fragments with the promise of trapping the naive immune repertoire in vitro.Read More…
One of the most important fundamental technologies in antibody production is hybridoma technology, development of which opens up the field of therapeutic antibodies development. Hybridoma technology firstly be described by Köhler andRead More…