In a new study, researchers from Zhejiang University, the Chinese Academy of Sciences, and Xiamen University have developed a novel approach to combat cancerous tumors. The method, named ONCOTECH, combines oncolytic virusRead More…
Swine Pseudorabies Virus Attenuated Vaccine Shows Potential for Oncolytic Therapy Against Malignant Tumors
Cancer is an increasingly severe global public health issue, with an urgent need for new anticancer drugs. Recent studies have identified oncolytic viruses as a relatively new class of cancer immunotherapy. OncolyticRead More…
Oncolytic Virus Therapy CAN-3110 Shows Promise in Treating Aggressive Brain Cancer Glioblastoma
Glioblastoma (GBM) is an aggressive brain cancer known for its resistance to treatment, with patients experiencing recurrent GBM having a survival period of less than 10 months. Immunotherapy, which mobilizes the body’sRead More…
Research Reveals New Mechanism of Oncolytic Virus M1 Enhancing DC Vaccine’s Anti-Tumor Effect
Immunotherapy has garnered significant attention due to its potential in achieving long-term control of tumor progression and extending the survival of patients in cancer treatment. Dendritic cells (DCs), known as the mostRead More…
Oncolytic Viruses Can Induce A “Cold” Tumor to Heat Up and Improve the Efficiency of Immunotherapy in Treating Cancer
Although checkpoint blockade therapy has achieved widespread success, it relies on reactive immune infiltration. Therefore, researchers are urgently seeking to develop therapies that enhance immune infiltration and prevent immune suppression. In aRead More…
The Secrets of Tissue-Resident Memory T Cells in Fighting Infections and Cancer
The human immune system possesses a remarkable strategy—it remembers past adversaries through a phenomenon known as immunological memory, thus thwarting potential diseases. This credit goes to a specialized cell type called tissue-residentRead More…
Scientists Reveal a Unique Mechanism of Gene Expression Coordination in Tumors
The tumor microenvironment (TME) plays a crucial role in cancer progression, and it is highly complex with variations among different patients. In a recent research report published in the international journal ScienceRead More…
Unveiling the Key Mechanism of p53 in Tumor Suppression
According to the latest data released by the International Agency for Research on Cancer (IARC), there were 19.29 million new cancer cases worldwide in 2020, with 9.96 million new cancer-related deaths. CancerRead More…
The Role of AXL in Cancer: A Modulator of Drug Resistance and Therapeutic Target
Cancer continues to be a leading cause of death worldwide, with its incidence and burden of mortality steadily on the rise. Despite significant advancements in research and development of cancer treatment strategiesRead More…
Novel AAV-Based Immunotherapy May Help Immune System Clear Glioblastoma
Glioblastomas are aggressive brain tumors that are largely resistant to immunotherapy, perhaps related to immunosuppression and dysfunctional tumor vasculature, which tend to impede T-cell infiltration. LIGHT, which is also known as tumorRead More…