Nef is an accessory protein encoded by HIV-1, HIV-2, and other primate lentiviruses and is closely related to viral replication, persistent infection, and the development of AIDS. Nef interacts with a varietyRead More…
The field of drug discovery is witnessing a revolutionary shift with the advent of Proteolysis Targeting Chimeras (PROTACs). This innovative therapeutic strategy is redefining how we approach the degradation of proteins, especiallyRead More…
On December 14, 2020, Arvinas, a pioneer of PROTAC, announced the results of phase I clinical trials of new PROTAC drugs ARV-471 and ARV-110, of which ARV-471 showed outstanding efficacy in patientsRead More…
In addition to the T-cell Lymphoma,T-cell Acute Lymphoblastic Leukaemia mentioned in our previous article, there are also related studies of protac in other blood diseases. Next, let’s analyze the research of protacRead More…