Introduction to HER2 targets Human epidermal growth factor receptor 2 (HER2), also known as ERBB2, is a receptor tyrosine kinase that belongs to the ERBB receptor tyrosine kinase family together with HER1Read More…
As a type of antibody with good application prospects, single domain antibodies have advantages in the diagnosis and treatment of many diseases. However, its short half-life in plasma limits its application inRead More…
With the advent of recombinant DNA technology, many antibody fragments have been developed. Among them, camelid heavy chain variable domains (VHHs) and single chain variable domains (ScFv) are the most favored variableRead More…
GPCR (G Protein-Coupled Receptor), the largest membrane protein family in mammalian genomes, is widely distributed in the central nervous system, immune system, cardiovascular system, and other organs and tissues, and participates inRead More…
Compared with traditional antibodies, single-domain antibodies (sdAbs) have small molecular weight, high hydrophilicity, and can be recombinantly expressed in vitro and mass-produced in E. coli, which can effectively avoid the difference betweenRead More…
In 1993, Professor Hamers-Casterman, an immunologist at the Free University of Brussels in Belgium, and his colleagues discovered a new type of antibody in camel serum, which is different from traditional antibodyRead More…