Nowadays, immunotherapy has shown great potential in treating human cancer, but it is not effective for all tumor types and only works for less than 3% of pancreatic ductal adenocarcinoma (PDAC) patients.Read More…
Oncolytic Virus Enlisted as a Helper to Hance DC Vaccine’s Anti-tumor Potency
Recently, a research paper titled “Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine” was published in Cell Reports Medicine, a sub-journal of Cell.Read More…
TLR9 Agonists Can Act as In-situ Anti-tumor Vaccines
Osteosarcoma (OS) is a highly malignant mesenchymal tumor composed of cells that produce bone-like and immature bone tissue. The peak incidence occurs in the second decade of life after birth. Although relativelyRead More…
An Alzheimer’s Disease Vaccine Targeting Senescence-associated Glycoproteins Has Been Developed
The American Heart Association’s Basic Cardiovascular Sciences Annual Conference in 2023, recently held in Boston, USA, featured a study indicating that a novel vaccine targeting inflammatory brain cells associated with Alzheimer’s diseaseRead More…
Cell: Novel Vaccine Technology Generates More Antibodies Against SARS-CoV-2 in Mice
In a recent study, the California Institute of Technology’s novel technology seeks to develop more effective vaccines, starting with SARS-CoV-2, the coronavirus that causes COVID-19. In mouse studies, this prototype vaccine producedRead More…
Novel mRNA Discovered—Possessing Adjuvant Function for Improved Cancer Vaccine
The mRNA COVID-19 vaccine has allowed us to witness the effectiveness, safety, and tremendous potential of mRNA technology. Currently, research institutions worldwide are targeting cancer as the next goal for mRNA technology.Read More…
Nature: Development of a New Oral Vaccine to Help Eradicate Polio
Despite conducting some of the most successful international vaccination campaigns in history, the poliovirus continues to circulate worldwide, posing a threat of neurological damage and paralysis to unvaccinated individuals. While wild poliovirusRead More…
Advanced Science: Cancer Vaccine Based on Tumor Cells or Tumor Cell/Tissue Lysate
Cancer vaccines are one of the most important methods of cancer immunotherapy. The three main factors that determine the efficacy of cancer vaccines are antigen, adjuvant, and formulation. Antigens induce specific immuneRead More…
JEM: Scientists use “Natural Systems” to Identify Specific Proteins that Have the Potential to Develop an Efficient HIV Vaccine
According to WHO data, since the identification of the cause of acquired immunodeficiency syndrome (AIDS) in 1984, the human immunodeficiency virus (HIV) has infected more than 80 million people and caused 40Read More…
The Protection Mechanism of mRNA Vaccines Against Monkeypox Virus
Recently, SCIENCE CHINA Life Sciences published a collaborative research paper entitled “Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity”. In this study,Read More…