Using nucleoside modified mRNAs in lipid nanoparticles (mRNA-LNP) as a vaccine for COVID-19 may successfully predict a new era of vaccine development. For HIV-1, polyvalent enveloped trimer protein nanoparticles may be usedRead More…
Recently, the US Food and Drug Administration (FDA) has granted respiratory syncytial virus (RSV) bivalent pre-fused F subunit vaccine (RSVpreF) breakthrough therapy recognition (BTD), which is an active immunization for the pregnantRead More…
Nearly 40 years after the discovery of HIV, it has killed 36.3 million people, but so far there is still no effective vaccine available. In a new study, however, researchers from theRead More…
Viruses such as HIV or hepatitis C virus (HCV) can destroy the immune system. So far, one way to develop vaccines against these chronic infections is to target memory B cells, aRead More…
Tumor vaccine is a promising therapeutic strategy, which produces long-term anti-tumor immunity by stimulating immune responses accordingly. However, due to inefficient vaccination, the clinical efficacy of such vaccines is limited. Recently, inRead More…
Researchers at the Cleveland Clinic in the United States launched a new vaccine study aimed at eventually preventing triple negative breast cancer, a highly invasive and deadly form of cancer. The vaccineRead More…
With the mounting number of drug-resistant microbial infections, the epidemic outbreak of pathogenic bacteria, and the possible threat of new organisms in the future, the clinical intervention of infectious diseases is facingRead More…
In the clinical trial of oncolytic vesicular stomatitis virus expressing interferon-β (VSV-IFN-β), a large group of patients initially achieved a preliminary response, but then the disease relapsed. A few days ago, inRead More…
In a recent study, researchers from the University of Southampton in the UK inserted a gene into a harmless bacteria that allowed it to stay in the nose for a long timeRead More…
mRNA vaccine is to transfer RNA to the cells of the body to express and produce protein antigens, so as to induce the body to produce an immune response against the antigen,Read More…