Immune Checkpoint Stable Cell Line Products

Introduction Features Applications Featured Products

Creative Biolabs offers immune checkpoint stable cell lines that have been modified to express specific immune checkpoint proteins consistently. These cell lines serve as invaluable tools for the research and development of immune checkpoint inhibitors.

Introduction

Immune checkpoints are regulatory processes in the immune system that either activate or suppress immunological responses. They are essential for maintaining self-tolerance and preventing autoimmunity by controlling the magnitude and duration of immune responses. However, cancer cells can use these pathways to elude the immune system, resulting in tumor development and progression.

Features of Immune Checkpoint Stable Cell Lines

Consistency: These cell lines reliably express the desired immune checkpoint proteins, allowing for repeatable and consistent experimental results.
Relevance: They provide a physiologically relevant model for studying immune responses and the effects of potential drugs.
Versatility: Suitable for various applications, including drug screening, genetic studies, and immunotherapy development.

Applications of Immune Checkpoint Stable Cell Lines

Drug Discovery: Immune checkpoint stable cell lines are widely used in drug discovery to identify and develop compounds that can modulate immune response via checkpoint pathways. This is particularly important in the development of novel cancer immunotherapies.
Mechanistic Studies: These cell lines facilitate mechanistic studies to understand how different checkpoints function and how their dysregulation may contribute to diseases.
Immune Response Modulation: By manipulating immune checkpoints in these stable cell lines, researchers can explore new ways to enhance the immune system's ability to recognize and destroy cancer cells or control pathological immune responses in autoimmune diseases.

Featured Products of Immune Checkpoint Stable Cell Lines

Cat#	Product Name	Species	Host Cell Type
S01YF-1022-KX161	Magic™ Human PD-L1 HEK293 Cell Line, Binding assay	Human	HEK293
S01YF-1222-KX893	Magic™ Human TNFRSF4 HT1080 Cell Line with NFkb-Luc2 Reporter	Human	HT1080
S01YF-1222-KX896	Magic™ Human CD274 Jurkat Cell Line with NFAT-Luc2 Reporter	Human	Jurkat
S01YF-0123-KX9	Magic™ Human PDCD1 HH Cell Line	Human	HH
S01YF-0123-KX11	Magic™ Human PDCD1 H22 Cell Line	Human	H22
S01YF-0123-KX14	Magic™ Cyno CTLA4 (delta23) HEK293T Cell Line	Cyno	HEK293T
S01YF-0123-KX16	Magic™ Human CD274 & PVR CT26 Cell Line	Human	CT26
S01YF-0123-KX17	Magic™ Cyno PDCD1 HEK293T Cell Line	Cyno	HEK293T
S01YF-0123-KX30	Magic™ Human EPCAM ID8 Cell Line	Human	ID8
Please learn more about immune checkpoint stable cell lines.

Immune checkpoint stable cell lines are vital tools in the field of immunology and oncology research. They play a critical role in advancing therapeutic strategies for cancer and other immune-related diseases. Creative Biolabs can offer immune checkpoint stable cell line products and customized services. Please feel free to contact us for more information.

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

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