This product is an ELISA kit for the determination of Pig Complement Factor B in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Pig Complement Factor B as low as 0.312 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Assay Type | Sandwich ELISA |
Sensitivity | 0.312 ng/mL (0.312-20 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Porcine |
Target | Factor B |
Cross Reactivity | No significant cross-reactions have been observed between Pig Complement Factor B and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | The storage of components varies. Please refer to the instructions for details. |
Introduction | Complement factor B is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. It also involves in cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|-Xaa bond in complement component C5 alpha-chain to yield C5a and C5b. |