C3

Clear All
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-30
Isotype IgG1
Applications ELISA; WB
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone CTJS-139
Isotype IgG2a
Applications FC; IA; IF; IHC; IP;
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-85
Isotype IgG1
Applications WB; ELISA; FC; IF; IHC
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-500
Isotype IgG2a Kappa
Applications WB; ELISA; IHC
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-774
Isotype IgG1κ
Applications ELISA; IP; AP
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-661
Isotype IgG1
Applications WB; IA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-66
Isotype IgG2b Kappa
Applications ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone CTJS-5
Isotype IgG2aκ
Applications WB; ELISA
Host Animal Rabbit
Specie Reactivity Human; Mouse
Isotype IgG
Applications WB; IF; IHC; IP
Host Animal Goats
Isotype IgG
Applications Western Blots; ELISA; Immunodiffusion
Host Animal Goats
Isotype IgG
Applications Immunodiffusion
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IP; IF; IHC; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications IP
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IHC; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; IHC; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-31
Isotype IgG1 Kappa
Applications WB; IF; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IP; IF; IHC; ELISA
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications IP
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IHC; ELISA
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; IHC; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; FCM
Host Animal Rat
Specie Reactivity Mouse
Antibody Clone TJL-32
Isotype IgG2a
Applications WB; IF; FCM
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-33
Isotype IgG1
Applications WB; IP
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-34
Isotype IgG1 Kappa
Applications WB; IP; IF; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-35
Isotype IgG2a Kappa
Applications WB; IP; IF; ELISA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-36
Isotype IgG1
Applications WB
Clear All
Specie Reactivity Human
Sensitivity 3.7 ng/mL (7.8-500 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 0.131 ng/mL (0.312-20 ng/mL)
Applications ELISA
Specie Reactivity Mouse
Sensitivity 23.44 ng/mL (93.75-6000 ng/mL)
Applications ELISA
Specie Reactivity Mouse
Sensitivity 1.39 ng/mL (3.12-200 ng/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 0.156 μg/mL (0.625-40 μg/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 1.37 ng/mL (3.12-200 ng/mL)
Applications ELISA
Specie Reactivity Rabbit
Sensitivity 27.3 ng/mL (27.3-7000 ng/mL)
Applications ELISA
Specie Reactivity Chicken
Sensitivity 6.9 ng/mL (15.63-1000 ng/mL)
Applications ELISA
[Cat#: CTK-126] Dog Complement C3 ELISA Kit
Specie Reactivity Dog
Sensitivity 0.195 µg/mL (0.78-50 µg/mL)
Applications ELISA
Specie Reactivity Goat
Sensitivity 0.23 µg/mL (0.9-60 µg/mL)
Applications ELISA
Specie Reactivity Ovine
Sensitivity 2.344 ng/mL (3.906-250 ng/mL)
Applications ELISA
Specie Reactivity Porcine
Sensitivity 1.33 ng/mL (3.12-200 ng/mL)
Applications ELISA
Specie Reactivity Porcine
Sensitivity 0.625 µg/mL (0.625-10 µg/mL)
Applications ELISA
Specie Reactivity Guinea Porcine
Sensitivity 1.875 ng/mL (3.125-200 ng/mL)
Applications ELISA
Specie Reactivity Bovine
Sensitivity 1.28 ng/mL (3.12-200 ng/mL)
Applications ELISA
Specie Reactivity Monkey
Sensitivity 4.69 ng/mL (7.81-500 ng/mL)
Applications ELISA
Specie Reactivity Canine
Sensitivity 1.875 ng/mL (3.125-200 ng/mL)
Applications ELISA
Specie Reactivity Monkey
Sensitivity 1.17 ng/mL (4.68-300 ng/mL)
Applications ELISA
Clear All
Specie Reactivity Human
Type Recombinant Protein
Expression Host Wheat Germ (in vitro)
Applications WB; ELISA; PA; AP
Specie Reactivity Human
Type Recombinant Protein Antigen
Expression Host E. Coli
Applications AC
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host Wheat Germ (in vitro)
Applications WB; ELISA; PA
Specie Reactivity Human
Type Native protein
Specie Reactivity Human
Type Native Protein
Applications Functional Assays
Specie Reactivity Cynomolgus Monkey
Type Native Protein
Applications Functional Assays
Specie Reactivity Mouse
Type Native Protein
Applications Functional Assays
Specie Reactivity Rat
Type Native Protein
Applications Functional Assays
Specie Reactivity Human
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA
Specie Reactivity Human
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Human
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA
Specie Reactivity Rat
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA
Specie Reactivity Rat
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Rat
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Bovine
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA
Specie Reactivity Pig
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
Specie Reactivity Pig
Type Recombinant Protein
Expression Host E.coli
Applications WB; ELISA; IP
[Cat#: CTMM-0123-MM31] Native Rabbit Complement C3 Protein
Specie Reactivity Rabbit
Type Native Protein
Applications Functional Assays
Specie Reactivity Human
Purity >90%
Applications Immunogen
Specie Reactivity Human
Purity >90%
Applications Immunogen
Purity >90%
Applications Immunogen
[Cat#: CTD-038] Complement C3 Peptide
Purity >90%
Applications Blocking
Specie Reactivity Human
Purity >90%
Applications Blocking
[Cat#: CTApt-722] Anti-C3 Aptamer
Affinity (Kd) <50nM
Chemical Modification RNA
[Cat#: CTMM-0124-RJ16] Anti-Human C3 Aptamer
Affinity (Kd) 1-50 nM
Chemical Modification 2'-fluoro pyrimidines
Clear All
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-AC-GFP
Tag GFP
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-Myc-DDK
Tag Myc-DDK
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-mGFP
Tag mGFP
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK
Tag Myc-DDK
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-mGFP
Tag mGFP
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Mouse
Type Expression Plasmid
Vector pCMV6-Entry
Specie Reactivity Mouse
Type Expression Plasmid
Vector pCMV6-AC-GFP
Tag GFP
Specie Reactivity Mouse
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Specie Reactivity Mouse
Type Expression Plasmid
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Mouse
Type Expression Plasmid
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Mouse
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Mouse
Type Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Rat
Type Expression Plasmid
Vector pCMV6-Entry
Specie Reactivity Rat
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Product List Background

Background

The complement system engages a tightly regulated network of plasma proteins, cell surface receptors, and regulators. In this system, complement C3 acts as a specifically versatile role via keeping the cascade alert, and it is a point of convergence of activation pathways, fueling the amplification of the complement response, exerting direct effector functions, and helping to coordinate downstream immune responses. Recently, some researches showed that naturally engages the power of C3 has important functions in many homeostatic processes, such as tissue regeneration and synapse pruning to clearing debris and controlling tumor cell progression. Meanwhile, due to its central position in immune surveillance, C3 became a target for microbial immune evasion and, if improperly engaged, a trigger point for a variety of clinical conditions.

C3 has displayed substantial correlations with obesity, and high gene expression of C3 has been reported in omental adipose tissue in obese men. Besides, it has been demonstrated that the cleavage product of C3, acylation-stimulating protein (ASP), is a paracrine metabolic factor that stimulates the uptake of glucose and fat storage in human adipose tissue. ASP deficiency in mice has been shown to be related to resistance to weight gain on a high-fat diet, despite improved food intake.

Fig. 1 Structure of the C3 protein. (By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=9444524)Fig. 1 C3 protein.1

Click the following targets to view our C3 product lists.

Reference

  1. By Emw - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=9444524
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For Research Use Only.