Name: Human B4GALT1 ELISA Matched Antibody Pair Set [ABP-Q-04-34]
SKU: ABP-Q-04-34
Price: 1120 USD

Human B4GALT1 ELISA Matched Antibody Pair Set [ABP-Q-04-34] (CAT#: ABP-Q-04-34)

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Human B4GALT1 antibody pair set for ELISA useCapture Antibody: rabbit anti-B4GALT1 monoclonal antibodyDetection Antibody: rabbit anti-B4GALT1 polyoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$1,120.00
Antibody Pair Set-Package 2	15 × 96 tests	$2,331.43

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	B4GALT1
Description	Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with α-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV01469
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Polyclonal
Host Species	Rabbit
Conjugation	HRP
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human B4GALT1 antibody pair set for ELISA use Capture Antibody: rabbit anti-B4GALT1 monoclonal antibody Detection Antibody: rabbit anti-B4GALT1 polyoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human B4GALT1
Range	156.25-10000 pg/mL
Research Area	Lipid metabolism
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	B4GALT1
Full Name	Beta-1,4-Galactosyltransferase 1
Background	This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.
Alternative Names	CDG2D
Gene ID	2683
Uniprot ID	P15291

For Research Use Only.

Human B4GALT1 ELISA Matched Antibody Pair Set [ABP-Q-04-34] (CAT#: ABP-Q-04-34)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview