Name: Human COMP ELISA Matched Antibody Pair Set [ABP-Q-04-110]
SKU: ABP-Q-04-110
Price: 919.6 USD

Human COMP ELISA Matched Antibody Pair Set [ABP-Q-04-110] (CAT#: ABP-Q-04-110)

Product Quick View

Human COMP antibody pair set for ELISA useCapture Antibody: mouse anti-COMP monoclonal antibodyDetection Antibody: mouse anti-COMP monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	COMP
Description	Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV01312
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Mouse
Conjugation	HRP
Clone	RD10111
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human COMP antibody pair set for ELISA use Capture Antibody: mouse anti-COMP monoclonal antibody Detection Antibody: mouse anti-COMP monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human COMP
Range	39.06-2500 pg/mL
Research Area	Extracellular Matrix
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	COMP
Full Name	Cartilage oligomeric matrix protein
Background	Cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5, is an extracellular matrix (ECM) protein primarily present in cartilage. In humans it is encoded by the COMP gene.
Alternative Names	COMP; EDM1; EPD1; MED; PSACH; THBS5; cartilage oligomeric matrix protein; TSP5
Gene ID	1311
Uniprot ID	P49747

For Research Use Only.

Human COMP ELISA Matched Antibody Pair Set [ABP-Q-04-110] (CAT#: ABP-Q-04-110)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview