Human CPB1 Matched Antibody Pair set for ELISA useCapture Antibody: Rabbit purified polyclonal anti-CPB1Detection Antibody: Mouse monoclonal anti-CPB1, IgG2a Kappa
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Antigen Detail | |
|---|---|
| Target | CPB1 |
| Description | Carboxypeptidase B (or peptidyl-L-lysine (-L-arginine) hydrolase) catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. It has been shown to be a single polypeptide of 34 kDa Da. Trypsin is capable of converting native enzyme to the active enzyme, carboxypeptidase B II in vitro. It can also be used as a serum marker for the diagnosis of acute pancreatitis. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Polyclonal |
| Host Species | Rabbit |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Mouse |
| Conjugation | Unconjugated |
| Clone | RD104 |
| Isotype | IgG2a, kappa |
| Purification | Affinity chromatography |
| Buffer | PBS, pH 7.4 |
General Product Property | |
|---|---|
| Product Overview | Human CPB1 Matched Antibody Pair set for ELISA use Capture Antibody: Rabbit purified polyclonal anti-CPB1 Detection Antibody: Mouse monoclonal anti-CPB1, IgG2a Kappa |
| Specificity | Validated for detecting natural and recombinant human CPB1 |
| Research Area | Metabolism |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Lyophilized |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | CPB1 |
| Full Name | Carboxypeptidase B1 |
| Background | Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008] |
| Alternative Names | Pancreatic Carboxypeptidase B; Carboxypeptidase B |
| Gene ID | 1360 |
| Uniprot ID | P15086 |
| HGNC | 2299 |
| Ensembl | ENSG00000153002 |
| OMIM | 114852 |
| Involvement in Disease | Diseases associated with CPB1 include Acute Pancreatitis and Pancreatitis. |
| Function | Carboxypeptidase B catalyzes the hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-terminal position of polypeptides. |
For Research Use Only.
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