Name: Human DKK1 ELISA Matched Antibody Pair Set [ABP-Q-04-136]
SKU: ABP-Q-04-136
Price: 919.6 USD

Human DKK1 ELISA Matched Antibody Pair Set [ABP-Q-04-136] (CAT#: ABP-Q-04-136)

Product Quick View

Human DKK1 antibody pair set for ELISA useCapture Antibody: mouse anti-Human DKK1 monoclonal antibodyDetection Antibody: mouse anti-Human DKK1 monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	DKK1
Description	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV01867
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Mouse
Conjugation	HRP
Clone	RD10190
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human DKK1 antibody pair set for ELISA use Capture Antibody: mouse anti-Human DKK1 monoclonal antibody Detection Antibody: mouse anti-Human DKK1 monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human DKK1
Range	39.06-2500 pg/mL
Research Area	Transplantation
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	DKK1
Full Name	dickkopf WNT signaling pathway inhibitor 1
Background	This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Alternative Names	Dkk-1; Dickkopf-1; SK; DKK-1; hDkk-1; Dickkopf-related protein 1
Uniprot ID	P07585

For Research Use Only.

Human DKK1 ELISA Matched Antibody Pair Set [ABP-Q-04-136] (CAT#: ABP-Q-04-136)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview