Human FTL ELISA Matched Antibody Pair Set [ABP-Q-04-173] (CAT#: ABP-Q-04-173)

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Human FTL antibody pair set for ELISA useCapture Antibody: Mouse anti-FTL monoclonal antibodyDetection Antibody: Rabbit anti-Human FTL polyclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Lot Number

Antigen Detail

TargetFTL
DescriptionFerritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Storage of iron in the tissues occurs in the form of ferritin and hemosiderin. The latter originates from ferritin that has undergone intracellular digestion of its protein shell, leaving the iron core. Ferritin and hemosiderin are components of a continuum. Ferritin has been identified in all types of living organisms: animals, plants, molds, and bacteria. Whithin the protein shell of ferritin, iron is first oxidized to the ferric state for storage as ferric oxyhdroxide. Thus, ferritin removes excess iron from the cell sap where it could otherwise participate in peroxidation mechanisms.
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesMouse
CloneIV01570
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityPolyclonal
Host SpeciesRabbit
ConjugationHRP
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewHuman FTL antibody pair set for ELISA use
Capture Antibody: Mouse anti-FTL monoclonal antibody
Detection Antibody: Rabbit anti-Human FTL polyclonal antibody conjugated to HRP
SpecificityQuantitative determination of Human FTL
Range46.88-3000 pg/Ml
Research AreaNeurodegenerative disease
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolFTL
Full NameFerritin Light Chain
BackgroundThis gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
Alternative NamesNeurodegeneration With Brain Iron Accumulation 3
Gene ID2512
Uniprot IDP02792

For Research Use Only.

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