Name: Human ICAM-1 ELISA Matched Antibody Pair Set [ABP-Q-04-188]
SKU: ABP-Q-04-188
Price: 919.6 USD

Human ICAM-1 ELISA Matched Antibody Pair Set [ABP-Q-04-188] (CAT#: ABP-Q-04-188)

Product Quick View

Human ICAM-1 antibody pair set for ELISA useCapture Antibody: mouse anti-ICAM-1 monoclonal antibodyDetection Antibody: rabbit anti-ICAM-1 polyclonal antibody conjugated to HRP

(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)

Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

Antigen Detail
Target	ICAM-1
Description	Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM-1 is a ligand for LFA-1(integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM-1 possesses binding sites for some immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM-1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease. Previous studies have shown that ICAM-1 is involved in inflammatory reactions and that a defect in ICAM-1 gene inhibits allergic contact hypersensitivity.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Mouse
Clone	IV01887
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Polyclonal
Host Species	Rabbit
Conjugation	HRP
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human ICAM-1 antibody pair set for ELISA use Capture Antibody: mouse anti-ICAM-1 monoclonal antibody Detection Antibody: rabbit anti-ICAM-1 polyclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human ICAM-1
Range	4.69-300 pg/mL
Research Area	Cell Type Markers
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	ICAM1
Full Name	Intercellular Adhesion Molecule 1
Background	ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene.[5][6] This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium.
Alternative Names	ICAM1; BB2; CD54; P3.58; intercellular adhesion molecule 1
Gene ID	3383
Uniprot ID	3383

For Research Use Only.

Human ICAM-1 ELISA Matched Antibody Pair Set [ABP-Q-04-188] (CAT#: ABP-Q-04-188)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview