Name: Human IL12B ELISA Matched Antibody Pair Set [ABP-Q-04-205]
SKU: ABP-Q-04-205
Price: 919.6 USD

Human IL12B ELISA Matched Antibody Pair Set [ABP-Q-04-205] (CAT#: ABP-Q-04-205)

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Human IL12B antibody pair set for ELISA useCapture Antibody: rabbit anti-Human IL12B monoclonal antibodyDetection Antibody: mouse anti-Human IL12B monoclonal antibody conjugated to HRP

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Type	Size	Price	Quantity
Antibody Pair Set-Package 1	5 × 96 tests	$919.60
Antibody Pair Set-Package 2	15 × 96 tests	$1,919.66

Datasheet

MSDS

Certificate of Analysis Lookup

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Lot Number

Antigen Detail
Target	IL12B
Description	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. IL12B/IL-12B associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine that functions in innate and adaptive immunity.
Species Reactivity	Human

Capture Antibody
Capture Clonality	Monoclonal
Host Species	Rabbit
Clone	IV01370
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, pH 7.4
Application	ELISA

Detection Antibody
Det-Clonality	Monoclonal
Host Species	Mouse
Conjugation	HRP
Clone	RD10466
Purification	Affinity Chromatography
Buffer	Prior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property
Product Overview	Human IL12B antibody pair set for ELISA use Capture Antibody: rabbit anti-Human IL12B monoclonal antibody Detection Antibody: mouse anti-Human IL12B monoclonal antibody conjugated to HRP
Specificity	Quantitative determination of Human IL12B
Range	15.63-1000 pg/mL
Research Area	Innate Immunity
Application	ELISA
Application Notes	Optimal dilutions should be determined experimentally by the user.
Form	Lyophilized
Storage	Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size	1 Set
Sample Type	Serum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage Statement	Available for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview
Gene Symbol	IL12B
Full Name	Interleukin-12 subunit beta
Background	Subunit beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit p40)[4] is a protein that in humans is encoded by the IL12B gene. IL-12B is a common subunit of interleukin 12 and Interleukin 23.
Alternative Names	IL12B; CLMF; CLMF2; IL-12B; IMD28; NKSF; NKSF2; IMD29; Interleukin 12 subunit beta; interleukin 12B
Gene ID	3593
Uniprot ID	P29460

For Research Use Only.

Human IL12B ELISA Matched Antibody Pair Set [ABP-Q-04-205] (CAT#: ABP-Q-04-205)

Antigen Detail

Capture Antibody

Detection Antibody

General Product Property

Target Overview