Human METTL1 ELISA Matched Antibody Pair Set [ABP-Q-04-274] (CAT#: ABP-Q-04-274)

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Human METTL1 antibody pair set for ELISA useCapture Antibody: mouse anti-Human METTL1 monoclonal antibodyDetection Antibody: mouse anti-Human METTL1 monoclonal antibody conjugated to HRP

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Type Size Price Quantity  
Antibody Pair Set-Package 1 5 × 96 tests $1,120.00
Antibody Pair Set-Package 2 15 × 96 tests $2,331.43
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Lot Number

Antigen Detail

TargetMETTL1
DescriptiontRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. METTL1 gene has been identified by its sequence similarity to the yeast ORF YDL21w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequence similarities to putative proteins from mouse, Drosophila melanogaster, Arabidopsis thaliana, Caenorhabditis elegans, and yeast (39.8% identity between all six species). Computer analyses of the deduced protein sequence reveal two highly conserved amino acid motifs, one of which is typical for methyltransferases. Both motifs are also present in hypothetical proteins from eubacteria. Disruption of the homologous yeast ORF YDL21w shows that the gene is at least not essential for vegetative growth in Saccharomyces cerevisiae.
Species ReactivityHuman

Capture Antibody

Capture ClonalityMonoclonal
Host SpeciesMouse
CloneIV01675
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, pH 7.4
ApplicationELISA

Detection Antibody

Det-ClonalityMonoclonal
Host SpeciesMouse
ConjugationHRP
CloneRD1074
PurificationAffinity Chromatography
BufferPrior to lyophilization: PBS, containing 50 % HRP-Protector

General Product Property

Product OverviewHuman METTL1 antibody pair set for ELISA use
Capture Antibody: mouse anti-Human METTL1 monoclonal antibody
Detection Antibody: mouse anti-Human METTL1 monoclonal antibody conjugated to HRP
SpecificityQuantitative determination of Human METTL1
Range156.25-10000 pg/mL
Research AreaTranslation
ApplicationELISA
Application NotesOptimal dilutions should be determined experimentally by the user.
FormLyophilized
StorageAvoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage.
Size1 Set
Sample TypeSerum; Supernatant; Urine; Cell lysate; Plasma; Tissue Homogenates
Usage StatementAvailable for Research Use Only. Not for use in therapeutic or diagnostic applications.

Target Overview

Gene SymbolMETTL1
Full NameMethyltransferase Like 1
BackgroundThis gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.
Alternative NamesC12orf1; TRMT8
Gene ID4234
Uniprot IDQ9UBP6

For Research Use Only.

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