Human S100A1 antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Unconjugated-Rabbit Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | S100A1 |
| Description | S100A1, also known as S100 calcium binding protein A1, is a protein encoded by the S100A1 gene in humans. S100A1 is highly expressed in myocardium and skeletal muscle, and is located in the Z disk and sarcoplasmic reticulum. S100A1 has been shown to be a promising candidate for gene therapy to treat cardiac tissue after myocardial infarction. |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV0178 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Clone | RD10275 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, BSA and Azide free |
General Product Property | |
|---|---|
| Product Overview | Human S100A1 antibody pair set for sandwich ELISA use Capture Antibody: Monoclonal IgG Detection Antibody: Unconjugated-Rabbit Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with Human S100A1. |
| Research Area | Immunology; Cell Biology; Cancer; Inflammation |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | S100A1 |
| Full Name | S100 calcium-binding protein A1 |
| Background | S100A1, also known as S100 calcium binding protein A1, is a protein encoded by the S100A1 gene in humans. S100A1 is highly expressed in myocardium and skeletal muscle, and is located in the Z disk and sarcoplasmic reticulum. S100A1 has been shown to be a promising candidate for gene therapy to treat cardiac tissue after myocardial infarction. |
| Alternative Names | S100A1; S100; S100-alpha; S100A; S100 calcium-binding protein A1; S100 calcium binding protein A1 |
| GeneCards | S100A1 |
| HGNC | 10486 |
| Ensembl | ENSG00000160678 |
| OMIM | 176940 |
| Involvement in Disease | Diseases associated with S100A1 include Epidermoid Cysts and Myoepithelioma. |
| Function | Probably acts as a Ca(2+) signal transducer (PubMed:22399290). In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change (PubMed:23351007). This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity. |
For Research Use Only.
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