Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone I1C1R122-2). We employs the AAV (EF1α-mCherry-NF-κB-EcoRI) vector components and the SynExpress system of the single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
CD22
Clone
I1C1R122-2
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.91
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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