Description
This product utilizes CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone I1C1R22-22). We employs the AAV (CMV-GFP-IL-10-KpnI) vector components and the SynExpress system of the single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
CD22
Clone
I1C1R22-22
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
GFP
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.85
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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