Description
This product utilizes CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone I1C1R22-28). We employs the AAV (EF1α-Cy3-NF-κB-BamHI) vector components and the SynExpress system of the lncRNA Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
CD22
Clone
I1C1R22-28
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
Cy3
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.88
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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