Description
This product utilizes CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD22 ( clone IRO324). We employs the Adenovirus (pL-GFP-IL-10-SaII) vector components and the SynExpress system of the single base pair Base Editing/Positive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CD22
Clone
IRO324
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
GFP
Promoter
pL
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
Adenovirus
Transformation Accuracy
0.88
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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