Brief Summary

Epitopes are the immunogenic antigen peptides, continuous or noncontinuous amino acid sequences, recognized by immune cells. Understanding cancer immunotherapy, as well as developing vaccines and targeted therapies, requires a thorough understanding of the molecular characteristics of epitopes within cancer antigens. Cellular and humoral immunity are validated to provide principal protection after epitope recognition. CD4+ and CD8+ T cells could separately recognize pathogenic epitopes presented by MHC I and MHC II molecules on antigen-presenting cells. BCRs and antibodies bind to the exposed solvent parts of the antigen. With rich knowledge and experience in immune responses of B cells and T cells to antigen/epitope, Creative Biolabs offers various B cell and T cell-based assays for cancer epitope analysis.

Our Capabilities

We can detect the epitope-specific adaptive immune responses based on antigen-specific receptors expressed on the surfaces of T- and B-lymphocytes using advanced equipment and technologies. Our services include:

• T Cell Epitopes and B Cell Epitopes Analysis
• Linear and Conformational Epitopes Analysis
• In Vitro Assays and In Vivo Assays

Specific Services

Immune cell types and cell biological activities are used to categorize services. Depending on your subject, you can use a single assay or a combination of assays to analyze cancer epitopes. We offer the following assay services. If you do not see any services that suit your needs, please contact us for a personalized inquiry.

Our Advantages

Fig.2 Our strengths in cancer epitope analysis. (Creative Biolabs)

Creative Biolabs is a reliable service provider with thousands of satisfied customers and a trusted partner for antigen epitope discovery. We collaborate closely with our clients and provide tailored solutions to meet their specific needs. If you are interested in our services, please contact us so that we can discuss your project with our skilled professionals.

References

1. Koşaloğlu-Yalçın, Z.; et al. The Cancer Epitope Database and Analysis Resource (CEDAR). Nucleic acids research. 2023, 51(D1): D845–D852.
2. Wells, D. K.; et al. Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction. Cell. 2020, 183(3): 818–834.e13.

For Research Use Only | Not For Clinical Use

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