Short Decsription
This product is a Glc-targeted RNA modification and metabolomics analysis tool based on the m1A (NSUN1-ALYREF-ALKBH1-HDACs-spacer C18) modification and PPP-mediated (hnRNPs-Lactyl-CoA-ATP) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-m1A-NSUN1-ALYREF-ALKBH1-HDACs-spacer C18
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Ovarian Cancers
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
PPP-hnRNPs-Lactyl-CoA-ATP