HeLa In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress) (CAT#: ITS-1022-YF5223)

HeLa

Human

In 1952, HeLa cells became the first human cell line that could grow and divide endlessly in a laboratory, leading scientists to label these cells "immortal". The immortality of HeLa cells contributed to their adoption across the world as the human cell line of choice for biomedical research.

Cervical Cancer

Oncology

In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

HeLa-cell based In Vitro ABTS Radical Cation Decolorization Assay (Oxidative Stress)

It's a commonly used simple antioxidant assay. The ability of antioxidants to reduce ABTS free radical (ABTS.) to ABTS is measured in the ABTS assay.

Oxidative Stress Assays

Disturbance between the production of reactive oxygen species (ROS), free radicals and antioxidant mechanisms is defined as the oxidative stress, or more precisely, it is an imbalance between the oxidant and antioxidant state in cells. This imbalance can cause harmful effects to cells and biomolecules, which ultimately causes adverse effects in the whole organism. Oxidative imbalance can target important proteinsand lipids in cells, which can increase the risk of developing a cancer. On the other hand, increased ROS production in cancer cells by certain cancer drugs can also arrest cancer cell cycle and cause senescence and apoptosis through oxidative stress.

Antioxidant Assay