Histology Assay - Skin malignant melanoma tissue microarray, 42 Cases/81 Cores (CAT#: ITS-1022-ZP1607)

Creative Biolabs has expertise in sample preparation for Immuno-Oncology histology services and immunohistochemistry (IHC). We understand that not all tissues are suitable for Immuno-Oncology studies. To support the specific tissue requirements for Immuno-Oncology projects, we have created a large range of FFPE blocks and custom Tumor Microarrays (TMAs) that have been specially selected for the presence of invasive margin, together with accompanying tumor/immune cell PD-L1 scores and TIL assessment (high/medium/low).

The services we provide as part of our Histology & IHC Platform are listed below:
- Standard & custom grossing
- Bone decalcification
- Standard & custom FFPE generation
- H&E Staining
- Marker optimization for IHC
- Slide Scanning
- TMA creation

Creative Biolabs Immuno-Oncology's histology and immunohistochemistry assay are custom developed and fully optimized to meet your needs in preclinical research. We also provide a comprehensive list of antibodies for IHC for your histology research. Contact us for more information.

- Expression, distribution and heterogeneity of novel I/O targets across multiple disease settings
- Examine novel I/O target expression in relation to tumor immune microenvironment e.g. checkpoint inhibitors
- Spatial relationships of I/O in tumor microenvironment
- Relate novel I/O target expression to tumor mutation status
- Identify disease segments most likely to respond toimmunotherapy
- Co-expression of I/O targets for rational immunotherapy combinations
- Biomarker development for patient selection

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH)