MHH-ES In Vitro Calcein AM Cytotoxic Assay (Cell Viability) (CAT#: ITS-1122-YF2107)

MHH-ES

Human

Human Ewings' sarcoma cell line established from the ascites of a 12-year-old Turkish boy with Ewing's sarcoma of the left pelvis (with peritoneal metastasis)

Ewing Sarcoma

Oncology

In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

MHH-ES-cell based In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

Calcein AM is another non-fluorescent cell permeable dye, which is converted to green-fluorescent calcein by viable intracellular esterases. Calcein violet AM, calcein red-orange, Oregon green 488 and 5-CFDA-AM are other examples of dyes used to monitor cell viability based on esterase activity in viable cells.

Cell Viability/Cytotoxicity and Antiproliferative Assays

Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.

Cell Viability Assay

Cell-based Viability Assays Based on Cellular Enzymes and Proteins