Assay Name
In Vitro Activator/Inhibitor Screening Assay
Short Description
Screen for activators or inhibitors of TLR9 signaling in a cellular context and characterize the biological activity of TLR9 and its interactions with ligands.
Assay Description
Creative Biolabs has developed several I-O function assay based on our stable cell Lines expressed the most popular immune checkpoints. TLR9 (Human) Activator/Inhibitor Screening Assay, HEK293 (TLR9 & NF-κB)-based is applied to screen for activators or inhibitors of TLR9 signaling in a cellular context and characterize the biological activity of TLR9 and its interactions with ligands. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.
Assay Alternative Names
In Vitro Activator/Inhibitor Screening Assay; Activator/Inhibitor Screening Assay
Assay Reporter
NF-κB Reporter
Assay Type
Activator/Inhibitor Screening Assay
Assay MOA
Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant HEK293 cell expressing firefly luciferase gene under the control of NF-κB response elements with constitutive expression of human TLR9 (Toll-like receptor 9, also been designated as CD289, a member of the toll-like receptor (TLR) family. GenBank Accession No. NM_017442). Which can be used in binding assays and functional assay.
Datasheet