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Magic™ Antibody Discovery - Cynomolgus B7-H2 / ICOSLG (19-256) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1032F)

Datasheet
This membrane protein is Cynomolgus B7-H2 / ICOSLG (19-256). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Cynomolgus
  • Target Protein
  • B7-H2 / ICOSLG
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 53.0 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Asp 19 - Thr 256 (Accession # XP_005548617.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • B7-H2 / ICOSLG
  • Full Name
  • inducible T cell costimulator ligand
  • Introduction
  • Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
  • Alternative Names
  • ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1, transmembrane protein B7-H2 ICOS ligand

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