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Magic™ Antibody Discovery - Human 2B4 / CD244 / SLAMF4 (22-221) Membrane Protein, Partial, -hIgG1 Fc -Avi tag, [Biotin] (CAT#: MP0894F)

Datasheet
This membrane protein is Human 2B4 / CD244 / SLAMF4 (22-221). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • 2B4 / CD244 / SLAMF4
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 50.7 kDa. As a result of glycosylation, the protein migrates as 65-80 kDa under reducing (R) condition, and 130-160 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Cys 22 - Arg 221 (Accession # NP_057466.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus, followed by a Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Conjugation
  • Biotin
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • 2B4 / CD244 / SLAMF4
  • Full Name
  • CD244 molecule
  • Introduction
  • This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • 2B4; NAIL; Nmrk; NKR2B4; SLAMF4; natural killer cell receptor 2B4; CD244 molecule, natural killer cell receptor 2B4; NK cell activation inducing ligand NAIL; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; SLAM family member 4; h2B4; signaling lymphocytic activation molecule 4

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