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Magic™ Antibody Discovery - Human BAFF / TNFSF13B / CD257 (140-285) Membrane Protein, Partial, hIgG1 Fc- tag (CAT#: MP0974F)

Datasheet
This membrane protein is Human BAFF / TNFSF13B / CD257 (140-285). It has been tested in SDS-PAGE, SEC-SEC-MALS, ELISA, SPR. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BAFF / TNFSF13B / CD257
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 76.7 kDa. The protein migrates as 120-140 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 140 - Leu 285 (Accession # Q9Y275-1) .

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SEC-SEC-MALS, ELISA, SPR
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
    >90% as determined by SEC-MALS.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • BAFF / TNFSF13B / CD257
  • Full Name
  • TNF superfamily member 13b
  • Introduction
  • The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
  • Alternative Names
  • DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20; tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; epididymis secretory sperm binding protein; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand 7A; tumor necrosis factor superfamily member 13b; tumor necrosis factor-like protein ZTNF4

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