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Magic™ Antibody Discovery - Human BMP-2 (284-396) Membrane Protein, Partial (CAT#: MP1049F)

Datasheet
This membrane protein is Human BMP-2 (284-396). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BMP-2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 12.8 kDa. the protein migrates as 14 kDa under reducing (R) condition, and 28 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Ala 284 - Arg 396 (Accession # NP_001191).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • E.coli
  • Tag
  • No tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >92% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 100 mM Acetic Acid, pH2.8. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • BMP-2
  • Full Name
  • bone morphogenetic protein 2
  • Introduction
  • This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
  • Alternative Names
  • BDA2; BMP2A; SSFSC; bone morphogenetic protein 2; bone morphogenetic protein 2A

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