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Magic™ Antibody Discovery - Human BTN3A1 / CD277 (30-254) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1019F)

Datasheet
This membrane protein is Human BTN3A1 / CD277 (30-254). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BTN3A1 / CD277
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 50.8 kDa. As a result of glycosylation, the protein migrates as 58-65 kDa under reducing (R) condition, and 120 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Gln 30 - Gly 254 (Accession # AAI21801).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • BTN3A1 / CD277
  • Full Name
  • butyrophilin subfamily 3 member A1
  • Introduction
  • The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).
  • Alternative Names
  • BTF5; BT3.1; CD277; BTN3.1; butyrophilin subfamily 3 member A1; dJ45P21.3 (butyrophilin, subfamily 3, member A1)

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