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Magic™ Antibody Discovery - Human CD14 (20-352) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1091F)

Datasheet
This membrane protein is Human CD14 (20-352). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD14
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 62.2 kDa. The protein migrates as 75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Thr 20 - Cys 352 (Accession # P08571-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD14
  • Full Name
  • CD14 molecule
  • Introduction
  • The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Alternative Names
  • CD14, CD14 molecule, CD14 antigen, monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein,

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