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Magic™ Antibody Discovery - Human CD155 / PVR (21-343) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1076F)

Datasheet
This membrane protein is Human CD155 / PVR (21-343). It has been tested in SDS-PAGE, ELISA, BLI, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD155 / PVR
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 61.7 kDa. The protein migrates as 95-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Trp 21 - Asn 343 (Accession # NP_006496.2).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA, BLI, FACS
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD155 / PVR
  • Full Name
  • PVR cell adhesion molecule
  • Introduction
  • The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene
  • Alternative Names
  • PVS; HVED; CD155; NECL5; TAGE4; Necl-5; poliovirus receptor; nectin-like protein 5

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