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Magic™ Antibody Discovery - Human CD30 / TNFRSF8 (19-379) Membrane Protein, Partial, -Llama IgG2b Fc tag, low endotoxin (CAT#: MP1104F)

Datasheet
This membrane protein is Human CD30 / TNFRSF8 (19-379). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD30 / TNFRSF8
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 66.3 kDa. The protein migrates as 95-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Phe 19 - Lys 379 (Accession # NP_001234.2).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Llama IgG2b Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <0.01 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD30 / TNFRSF8
  • Full Name
  • TNF receptor superfamily member 8
  • Introduction
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
  • Alternative Names
  • tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, cytokine receptor CD30, lymphocyte activation antigen CD30

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