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Magic™ Antibody Discovery - Human CD48 / SLAMF2 (27-220) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1278F)

Datasheet
This membrane protein is Human CD48 / SLAMF2 (27-220). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD48 / SLAMF2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 49.0 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 27 - Ser 220 (Accession # P09326-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD48 / SLAMF2
  • Full Name
  • CD48 molecule
  • Introduction
  • This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102; CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; CD48 antigen (B-cell membrane protein); SLAM family member 2; TCT.1; leukocyte antigen MEM-102; signaling lymphocytic activation molecule 2

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