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Magic™ Antibody Discovery - Human CNTF R alpha (23-346) Membrane Protein, Partial, -His tag (CAT#: MP1343F)

Datasheet
This membrane protein is Human CNTF R alpha (23-346). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CNTF R alpha
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 23 - Pro 346 (Accession # AAH01492).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CNTF R alpha
  • Full Name
  • ciliary neurotrophic factor receptor
  • Introduction
  • This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
  • Alternative Names
  • ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha

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