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Magic™ Antibody Discovery - Human DLL3 (27-492) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1357F)

This membrane protein is Human DLL3 (27-492). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • DLL3
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 75.0 kDa. The protein migrates as 50-60 kDa and 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • DLL3
  • Full Name
  • delta like canonical Notch ligand 3
  • Introduction
  • This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
  • Alternative Names
  • SCDO1; delta-like protein 3; delta-like 3; delta3; drosophila Delta homolog 3

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