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Magic™ Antibody Discovery - Human Ephrin-A1 / EFNA1 (19-182) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1376F)

Datasheet
This membrane protein is Human Ephrin-A1 / EFNA1 (19-182). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Ephrin-A1 / EFNA1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 46.0 kDa. As a result of glycosylation, the protein migrates as 53-57 kDa under reducing (R) condition, and 100-115 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Sequence
  • AA Asp 19 - Ser 182 (Accession # P20827-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Ephrin-A1 / EFNA1
  • Full Name
  • ephrin A1
  • Introduction
  • This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.
  • Alternative Names
  • B61; EFL1; GMAN; ECKLG; EPLG1; LERK1; LERK-1; TNFAIP4; ephrin-A1; TNF alpha-induced protein 4; eph-related receptor tyrosine kinase ligand 1; epididymis secretory sperm binding protein; gastric cancer metastasis associated long noncoding RNA; immediate early response protein B61; ligand of eph-related kinase 1; tumor necrosis factor, alpha-induced protein 4

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