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Magic™ Antibody Discovery - Human Fc gamma RIIIB/CD16-2 (17-200) Membrane Protein, Partial, -His -Avi tag, [Biotin] (CAT#: MP1431F)

Datasheet
This membrane protein is Human Fc gamma RIIIB/CD16-2 (17-200). It has been tested in SDS-PAGE, SPR, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Fc gamma RIIIB/CD16-2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 24.5 kDa. The protein migrates as 37-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gly 17 - Ser 200 (Accession # O75015).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, SPR, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus followed by an Avi tag
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Fc gamma RIIIB/CD16-2
  • Full Name
  • Fc fragment of IgG receptor IIIb
  • Introduction
  • The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
  • Alternative Names
  • CD16; FCG3; CD16A; CD16b; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb; low affinity immunoglobulin gamma Fc region receptor III-B; Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc gamma receptor III-B; Fc gamma receptor IIIb; Fc-gamma receptor IIIb (CD 16); fc-gamma RIII-beta; fc-gamma RIIIb; igG Fc receptor III-1

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