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Magic™ Antibody Discovery - Human Frizzled-2 / FZD2 (24-190) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0118F)

Datasheet
This membrane protein is Human Frizzled-2 / FZD2 (24-190). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Frizzled-2 / FZD2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 44.4 kDa. The protein migrates as 50-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 24 - Pro 190 (Accession # Q14332-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Frizzled-2 / FZD2
  • Full Name
  • frizzled class receptor 2
  • Introduction
  • This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
  • Alternative Names
  • Fz2; fz-2; fzE2; hFz2; OMOD2; frizzled-2; frizzled 2, seven transmembrane spanning receptor; frizzled family receptor 2; frizzled homolog 2

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