Close
Close

Magic™ Antibody Discovery - Human Frizzled-7 / FZD7 (33-185) Membrane Protein, Partial, -His tag (CAT#: MP0092F)

Datasheet
This membrane protein is Human Frizzled-7 / FZD7 (33-185). It has been tested in SDS-PAGE, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Frizzled-7 / FZD7
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 18.6 kDa. The protein migrates as 25-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 33 - Leu 185 (Accession # O75084-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization

Target

  • Target Protein
  • Frizzled-7 / FZD7
  • Full Name
  • frizzled class receptor 7
  • Introduction
  • Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
  • Alternative Names
  • FzE3; frizzled-7; Frizzled, drosophila, homolog of, 7
    frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; fz-7; hFz7

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us