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Magic™ Antibody Discovery - Human Galectin-3 (1-250) Membrane Protein, Partial, -His tag (CAT#: MP0140F)

Datasheet
This membrane protein is Human Galectin-3 (1-250). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Galectin-3
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 27.0 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE).
  • Sequence
  • AA Met 1 - Ile 250 (Accession # NP_002297).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • E.coli
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >92% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM HEPES, 150 mM NaCl, 5 mM EDTA, 2 mM TCEP, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Galectin-3
  • Full Name
  • galectin 3
  • Introduction
  • This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; galectin-3; 35 kDa lectin; IgE-binding protein; MAC-2 antigen; advanced glycation end-product receptor 3; carbohydrate-binding protein 35; epididymis secretory sperm binding protein; galactose-specific lectin 3; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3

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