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Magic™ Antibody Discovery - Human GFR alpha-like (19-351) Membrane Protein, Partial, -His tag (CAT#: MP0172F)

Datasheet
This membrane protein is Human GFR alpha-like (19-351). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GFR alpha-like
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 39.7 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ser 19 - Glu 351 (Accession # Q6UXV0-1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • GFR alpha-like
  • Full Name
  • GDNF family receptor alpha like
  • Introduction
  • Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
  • Alternative Names
  • GRAL; UNQ9356; C6orf144; bA360D14.1; GDNF family receptor alpha-like; IVFI9356

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