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Magic™ Antibody Discovery - Human HMGB1 (2-215) Membrane Protein, Partial, mIgG2a Fc- tag, low endotoxin (CAT#: MP0210F)

Datasheet
This membrane protein is Human HMGB1 (2-215). It has been tested in SDS-PAGE, Cell based assay. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HMGB1
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 51.6 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gly 2 - Glu 215 (Accession # P09429-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, Cell based assay
  • Expression Systems
  • HEK293
  • Tag
  • Mouse IgG2a Fc tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <0.1 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • HMGB1
  • Full Name
  • high mobility group box 1
  • Introduction
  • This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
  • Alternative Names
  • HMG1; HMG3; HMG-1; SBP-1; high mobility group protein B1; Amphoterin; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1

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